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The protection of EU citizens from pesticide cocktail effects, a legal and political commitment of the EU. EU citizens and the environment are continuously exposed to many different combinations of chemicals, including pesticide formulations, both in indoor and outdoor environments (food, water, air, etc.). On their own, synthetic pesticide formulations (or plant protection products) already raise significant concerns. However, a combined exposure to several of them is putting both human and environmental health even more at risk due to “cocktail effects”.